Job Description

Our companyis a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

We seek a highly motivated Research Scientist to join our Chemical Biology team to effectively enable high-throughput proteomics workflow development for target/MOA identification and validation. The successful candidate will enable the fast-increasing needs of automated Mass Spectrometry-based proteomics sample preparation workflows development, reiterative testing and optimization. This scientist will work closely with proteomics team and colleagues in Chemistry, Pharmacology and Disease Area Biology functions to identify and quantify proteins from biologically relevant tissues, organs and cells. We seek scientists inspired by our mission that will fit well with the collaborative, rigorous and entrepreneurial spirit of our company culture.

Required Qualifications

• MS/BS degree in chemistry, biochemistry, biology, or related life sciences degree with a minimum of 3-5 years of hands-on lab-based experience (includes academic undergrad/graduate work)

• Experience in mammalian cell culture is required.

• The candidate should have excellent communication skills and ability to collaborate closely with scientists within the team to adapt and optimize workflows.

• The candidate is expected to work well in a team environment and contribute to the team deliverables with strong problem-solving skills, laboratory skills and exquisite attention to experimental details and record keeping.

Preferred Qualifications:

• Experience with 96-well plate and/or other high throughput assays highly preferred.

• The ideal candidate will be highly skilled in mammalian cell culture (at least 2 years of experience) to support: 1) culturing of diverse primary and cancer cell lines using different labware (from multi-layer flasks to 96-well plates); 2) Western Blot assays; 3) protein extraction and quantification from cell lines and tissues.

• Hands-on experience adapting, optimizing and/or developing multi-well assays (including compound treatment of cells in a 96-well format), prior experience with liquid handlers, sub-cellular fractionation and tissue homogenization protocols are preferred.

• Familiarity with chemical labeling techniques and mass spectrometry sample preparation workflows such as in-solution digestion and HPLC-based fractionation is highly desirable.

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Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R322285