Job Description

Job Description/Key Responsibilities:

The Screening & Compound Profiling group at our Research Laboratories site in Rahway, NJ is looking for a highly motivated individual with an extensive background in high-throughput screening to lead an Automation & Informatics team. Incumbent will manage a team of ~ten senior professionals executing biochemical & cellular High Throughput Screening (HTS) for target and lead discovery in a multi-disciplinary drug discovery environment enabling programs across oncology, immunology, neuroscience, cardiometabolic and infectious disease. In addition, incumbent will enable newer screening technologies (e.g. arrayed CRISPR, cell painting, mRNA-Display & high-throughput mass spectrometry) with 'at-scale' automation and ensure that data is captured, analyzed and curated in a manner enabling ML/AI (in partnership with IT). Incumbent will contribute to a high-performance culture of inclusion, collaboration, engagement and self-accountability and promote our external reputation by contributing to publications and participating in external symposia.

Education:

• Advanced Degree in Biomedical engineering, Pharmacological Sciences, Biochemistry, Cell Pharmacology or equivalent plus >10 (PhD) or >20 (MSc) years experience in HTS, Automation and Informatics in an industry/biotech setting.

Required Skills & Experience:

• Detailed interactions with therapeutic areas and chemistry across high-throughput screening, hit-to-lead and/or lead optimization discovery space.

• Subject matter expert in biochemical & cell-based high throughput assay development, miniaturization and automation across multiple platforms/modalities.

• Able to collaborate and thrive in a matrix team environment integrating automation, informatics, in vitro pharmacology and biology.

• Experienced in the acquisition and registration of samples across modalities including small molecules, peptides and CRISPR guides.

• Knowledge and experience working with CRO's, externalizing/internalizing projects/assays/reagents to solve for Capacity and Capabilities.

• Experience managing/developing scientists and a track record of successfully leading projects/teams to clear outcomes.

• Passion for fostering a diverse and inclusive culture and contributing to the growth and success of colleagues.

• Strong external reputation as evidenced through publications, presentations, and/or scientific community engagement.

• Excellent verbal, written and interpersonal communication skills with a proven track-record of maintaining strong relationships with stakeholders.

Preferred Skills and Experience:

• Demonstrated collaboration with data scientists and 'wet-lab' to optimally position foundational data for ML/AI.

• Knowledgeable in considerations leading to fit-for-purpose automation/informatics solutions e.g. prototypes, minimally viable products or sustainable, at-scale.

• Collaboration with project teams to develop innovative approaches to phenotypic screening for small molecule & functional genomic discovery efforts.

• Interaction with affinity-based screening teams/technologies (DEL, AS/MS, mRNA-Display) and adjacent functions (protein generation, biophysics).

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

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Travel Requirements:

Flexible Work Arrangements:

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Job Posting End Date:

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:09/27/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R312456